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Serotonin Syndrome. Serotonin syndrome is when There exists excessive of a substance named serotonin in Your system. Methadone might cause serotonin syndrome when it can be taken with other medicines that affect serotonin.

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Situations of serotonin syndrome, a likely existence-threatening issue, happen to be documented through concomitant use of METHADOSE with serotonergic medications. Discontinue METHADOSE if serotonin syndrome is suspected.

Similar to morphine in its analgesic outcome, it absolutely was initially used in medication to relieve severe pain. Methadone is Employed in the form of its hydrochloride salt, that is a white, crystalline powder with a bitter flavor. It truly is soluble in water, in Alcoholic beverages, and in chloroform.

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